WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:negative regulation of intracellular protein kinase cascade       ID:GO:0010741
C=124; O=5; E=0.63; R=7.97; rawP=0.0004; adjP=0.0428
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
2  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
3  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
4  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001
5  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209


Database:biological process       Name:regulation of cytokine production       ID:GO:0001817
C=378; O=8; E=1.91; R=4.18; rawP=0.0006; adjP=0.0428
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000172216 NA CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1051 ENSG00000172216
2  ENSG00000106100 NA NOD1 nucleotide-binding oligomerization domain containing 1 10392 ENSG00000106100
3  ENSG00000023445 NA BIRC3 baculoviral IAP repeat containing 3 330 ENSG00000023445
4  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
5  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
6  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
7  ENSG00000186141 NA POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 10623 ENSG00000186141
8  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001


Database:biological process       Name:negative regulation of growth       ID:GO:0045926
C=195; O=6; E=0.99; R=6.08; rawP=0.0005; adjP=0.0428
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000187193 NA MT1X metallothionein 1X 4501 ENSG00000187193
2  ENSG00000184205 NA TSPYL2 TSPY-like 2 64061 ENSG00000184205
3  ENSG00000135503 NA ACVR1B activin A receptor, type IB 91 ENSG00000135503
4  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001
5  ENSG00000205364 NA MT1M metallothionein 1M 4499 ENSG00000205364
6  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593


Database:biological process       Name:nucleotide-binding oligomerization domain containing signaling pathway       ID:GO:0070423
C=31; O=3; E=0.16; R=19.13; rawP=0.0005; adjP=0.0428
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000106100 NA NOD1 nucleotide-binding oligomerization domain containing 1 10392 ENSG00000106100
2  ENSG00000023445 NA BIRC3 baculoviral IAP repeat containing 3 330 ENSG00000023445
3  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906


Database:biological process       Name:negative regulation of I-kappaB kinase/NF-kappaB cascade       ID:GO:0043124
C=32; O=3; E=0.16; R=18.53; rawP=0.0006; adjP=0.0428
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
2  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
3  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906


Database:biological process       Name:positive regulation of defense response       ID:GO:0031349
C=225; O=7; E=1.14; R=6.15; rawP=0.0001; adjP=0.0428
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000106100 NA NOD1 nucleotide-binding oligomerization domain containing 1 10392 ENSG00000106100
2  ENSG00000186141 NA POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 10623 ENSG00000186141
3  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
4  ENSG00000023445 NA BIRC3 baculoviral IAP repeat containing 3 330 ENSG00000023445
5  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
6  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
7  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001


Database:biological process       Name:regulation of I-kappaB kinase/NF-kappaB cascade       ID:GO:0043122
C=196; O=6; E=0.99; R=6.05; rawP=0.0005; adjP=0.0428
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
2  ENSG00000106100 NA NOD1 nucleotide-binding oligomerization domain containing 1 10392 ENSG00000106100
3  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
4  ENSG00000152661 NA GJA1 gap junction protein, alpha 1, 43kDa 2697 ENSG00000152661
5  ENSG00000023445 NA BIRC3 baculoviral IAP repeat containing 3 330 ENSG00000023445
6  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906


Database:biological process       Name:interleukin-6 production       ID:GO:0032635
C=69; O=4; E=0.35; R=11.46; rawP=0.0004; adjP=0.0428
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000172216 NA CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1051 ENSG00000172216
2  ENSG00000106100 NA NOD1 nucleotide-binding oligomerization domain containing 1 10392 ENSG00000106100
3  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
4  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001


Database:biological process       Name:regulation of defense response       ID:GO:0031347
C=426; O=9; E=2.15; R=4.18; rawP=0.0003; adjP=0.0428
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000106100 NA NOD1 nucleotide-binding oligomerization domain containing 1 10392 ENSG00000106100
2  ENSG00000023445 NA BIRC3 baculoviral IAP repeat containing 3 330 ENSG00000023445
3  ENSG00000155849 NA ELMO1 engulfment and cell motility 1 9844 ENSG00000155849
4  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
5  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
6  ENSG00000027697 NA IFNGR1 interferon gamma receptor 1 3459 ENSG00000027697
7  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
8  ENSG00000186141 NA POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 10623 ENSG00000186141
9  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001


Database:biological process       Name:regulation of interleukin-6 production       ID:GO:0032675
C=67; O=4; E=0.34; R=11.80; rawP=0.0004; adjP=0.0428
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000172216 NA CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1051 ENSG00000172216
2  ENSG00000106100 NA NOD1 nucleotide-binding oligomerization domain containing 1 10392 ENSG00000106100
3  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
4  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001


Database:molecular function       Name:MRF binding       ID:GO:0043426
C=5; O=2; E=0.02; R=83.75; rawP=0.0002; adjP=0.0268
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000123095 NA BHLHE41 basic helix-loop-helix family, member e41 79365 ENSG00000123095
2  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514


Database:molecular function       Name:interleukin-1 receptor activity       ID:GO:0004908
C=7; O=2; E=0.03; R=59.82; rawP=0.0005; adjP=0.0335
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
2  ENSG00000115604 NA IL18R1 interleukin 18 receptor 1 8809 ENSG00000115604


Database:molecular function       Name:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity       ID:GO:0000982
C=84; O=3; E=0.40; R=7.48; rawP=0.0076; adjP=0.1045
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000172216 NA CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1051 ENSG00000172216
2  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
3  ENSG00000123095 NA BHLHE41 basic helix-loop-helix family, member e41 79365 ENSG00000123095


Database:molecular function       Name:cytokine receptor activity       ID:GO:0004896
C=81; O=3; E=0.39; R=7.75; rawP=0.0068; adjP=0.1045
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
2  ENSG00000027697 NA IFNGR1 interferon gamma receptor 1 3459 ENSG00000027697
3  ENSG00000115604 NA IL18R1 interleukin 18 receptor 1 8809 ENSG00000115604


Database:molecular function       Name:E-box binding       ID:GO:0070888
C=28; O=2; E=0.13; R=14.95; rawP=0.0078; adjP=0.1045
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000123095 NA BHLHE41 basic helix-loop-helix family, member e41 79365 ENSG00000123095
2  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094


Database:molecular function       Name:cytokine binding       ID:GO:0019955
C=60; O=3; E=0.29; R=10.47; rawP=0.0029; adjP=0.1045
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
2  ENSG00000027697 NA IFNGR1 interferon gamma receptor 1 3459 ENSG00000027697
3  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001


Database:molecular function       Name:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription       ID:GO:0001191
C=23; O=2; E=0.11; R=18.21; rawP=0.0053; adjP=0.1045
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
2  ENSG00000123095 NA BHLHE41 basic helix-loop-helix family, member e41 79365 ENSG00000123095


Database:molecular function       Name:RNA polymerase II core promoter proximal region sequence-specific DNA binding       ID:GO:0000978
C=24; O=2; E=0.11; R=17.45; rawP=0.0058; adjP=0.1045
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000123095 NA BHLHE41 basic helix-loop-helix family, member e41 79365 ENSG00000123095
2  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094


Database:molecular function       Name:transcription factor binding       ID:GO:0008134
C=432; O=7; E=2.06; R=3.39; rawP=0.0045; adjP=0.1045
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000172216 NA CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1051 ENSG00000172216
2  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
3  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
4  ENSG00000123095 NA BHLHE41 basic helix-loop-helix family, member e41 79365 ENSG00000123095
5  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
6  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
7  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779


Database:molecular function       Name:bHLH transcription factor binding       ID:GO:0043425
C=22; O=2; E=0.11; R=19.03; rawP=0.0049; adjP=0.1045
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000123095 NA BHLHE41 basic helix-loop-helix family, member e41 79365 ENSG00000123095
2  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514


Database:cellular component       Name:connexon complex       ID:GO:0005922
C=21; O=2; E=0.09; R=21.09; rawP=0.0040; adjP=0.3360
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000187513 NA GJA4 gap junction protein, alpha 4, 37kDa 2701 ENSG00000187513
2  ENSG00000152661 NA GJA1 gap junction protein, alpha 1, 43kDa 2697 ENSG00000152661


Database:cellular component       Name:gap junction       ID:GO:0005921
C=31; O=2; E=0.14; R=14.29; rawP=0.0086; adjP=0.3612
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000187513 NA GJA4 gap junction protein, alpha 4, 37kDa 2701 ENSG00000187513
2  ENSG00000152661 NA GJA1 gap junction protein, alpha 1, 43kDa 2697 ENSG00000152661


Database:cellular component       Name:plasma membrane part       ID:GO:0044459
C=1918; O=13; E=8.66; R=1.50; rawP=0.0876; adjP=0.5660
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000187513 NA GJA4 gap junction protein, alpha 4, 37kDa 2701 ENSG00000187513
2  ENSG00000156453 NA PCDH1 protocadherin 1 5097 ENSG00000156453
3  ENSG00000106100 NA NOD1 nucleotide-binding oligomerization domain containing 1 10392 ENSG00000106100
4  ENSG00000152661 NA GJA1 gap junction protein, alpha 1, 43kDa 2697 ENSG00000152661
5  ENSG00000205336 NA GPR56 G protein-coupled receptor 56 9289 ENSG00000205336
6  ENSG00000135503 NA ACVR1B activin A receptor, type IB 91 ENSG00000135503
7  ENSG00000101276 NA SLC52A3 solute carrier family 52, riboflavin transporter, member 3 113278 ENSG00000101276
8  ENSG00000136160 NA EDNRB endothelin receptor type B 1910 ENSG00000136160
9  ENSG00000108622 NA ICAM2 intercellular adhesion molecule 2 3384 ENSG00000108622
10  ENSG00000027697 NA IFNGR1 interferon gamma receptor 1 3459 ENSG00000027697
11  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
12  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001
13  ENSG00000148175 NA STOM stomatin 2040 ENSG00000148175


Database:cellular component       Name:cell       ID:GO:0005623
C=14644; O=71; E=66.12; R=1.07; rawP=0.0681; adjP=0.5660
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
2  ENSG00000129657 NA SEC14L1 SEC14-like 1 (S. cerevisiae) 6397 ENSG00000129657
3  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
4  ENSG00000155508 NA CNOT8 CCR4-NOT transcription complex, subunit 8 9337 ENSG00000155508
5  ENSG00000101276 NA SLC52A3 solute carrier family 52, riboflavin transporter, member 3 113278 ENSG00000101276
6  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
7  ENSG00000135821 NA GLUL glutamate-ammonia ligase 2752 ENSG00000135821
8  ENSG00000179604 NA CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 23580 ENSG00000179604
9  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001
10  ENSG00000117461 NA PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 8503 ENSG00000117461
11  ENSG00000069122 NA GPR116 G protein-coupled receptor 116 221395 ENSG00000069122
12  ENSG00000027697 NA IFNGR1 interferon gamma receptor 1 3459 ENSG00000027697
13  ENSG00000023445 NA BIRC3 baculoviral IAP repeat containing 3 330 ENSG00000023445
14  ENSG00000152661 NA GJA1 gap junction protein, alpha 1, 43kDa 2697 ENSG00000152661
15  ENSG00000135503 NA ACVR1B activin A receptor, type IB 91 ENSG00000135503
16  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
17  ENSG00000117707 NA PROX1 prospero homeobox 1 5629 ENSG00000117707
18  ENSG00000113384 NA GOLPH3 golgi phosphoprotein 3 (coat-protein) 64083 ENSG00000113384
19  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
20  ENSG00000196136 NA SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 12 ENSG00000196136
21  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
22  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
23  ENSG00000096060 NA FKBP5 FK506 binding protein 5 2289 ENSG00000096060
24  ENSG00000131386 NA GALNTL2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2 117248 ENSG00000131386
25  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
26  ENSG00000179921 NA GPBAR1 G protein-coupled bile acid receptor 1 151306 ENSG00000179921
27  ENSG00000171877 NA FRMD5 FERM domain containing 5 84978 ENSG00000171877
28  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593
29  ENSG00000187513 NA GJA4 gap junction protein, alpha 4, 37kDa 2701 ENSG00000187513
30  ENSG00000184205 NA TSPYL2 TSPY-like 2 64061 ENSG00000184205
31  ENSG00000143882 NA ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 245973 ENSG00000143882
32  ENSG00000163389 NA POGLUT1 protein O-glucosyltransferase 1 56983 ENSG00000163389
33  ENSG00000205336 NA GPR56 G protein-coupled receptor 56 9289 ENSG00000205336
34  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
35  ENSG00000157150 NA TIMP4 TIMP metallopeptidase inhibitor 4 7079 ENSG00000157150
36  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
37  ENSG00000187193 NA MT1X metallothionein 1X 4501 ENSG00000187193
38  ENSG00000115604 NA IL18R1 interleukin 18 receptor 1 8809 ENSG00000115604
39  ENSG00000135378 NA PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 79056 ENSG00000135378
40  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
41  ENSG00000105245 NA NUMBL numb homolog (Drosophila)-like 9253 ENSG00000105245
42  ENSG00000134369 NA NAV1 neuron navigator 1 89796 ENSG00000134369
43  ENSG00000123095 NA BHLHE41 basic helix-loop-helix family, member e41 79365 ENSG00000123095
44  ENSG00000205364 NA MT1M metallothionein 1M 4499 ENSG00000205364
45  ENSG00000183580 NA FBXL7 F-box and leucine-rich repeat protein 7 23194 ENSG00000183580
46  ENSG00000136160 NA EDNRB endothelin receptor type B 1910 ENSG00000136160
47  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
48  ENSG00000086544 NA ITPKC inositol-trisphosphate 3-kinase C 80271 ENSG00000086544
49  ENSG00000186141 NA POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 10623 ENSG00000186141
50  ENSG00000156313 NA RPGR retinitis pigmentosa GTPase regulator 6103 ENSG00000156313
51  ENSG00000221869 NA CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1052 ENSG00000221869
52  ENSG00000154217 NA PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 26207 ENSG00000154217
53  ENSG00000156453 NA PCDH1 protocadherin 1 5097 ENSG00000156453
54  ENSG00000118985 NA ELL2 elongation factor, RNA polymerase II, 2 22936 ENSG00000118985
55  ENSG00000164951 NA PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 54704 ENSG00000164951
56  ENSG00000162174 NA ASRGL1 asparaginase like 1 80150 ENSG00000162174
57  ENSG00000146457 NA WTAP Wilms tumor 1 associated protein 9589 ENSG00000146457
58  ENSG00000184005 NA ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 256435 ENSG00000184005
59  ENSG00000108622 NA ICAM2 intercellular adhesion molecule 2 3384 ENSG00000108622
60  ENSG00000082996 NA RNF13 ring finger protein 13 11342 ENSG00000082996
61  ENSG00000172216 NA CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1051 ENSG00000172216
62  ENSG00000101187 NA SLCO4A1 solute carrier organic anion transporter family, member 4A1 28231 ENSG00000101187
63  ENSG00000106100 NA NOD1 nucleotide-binding oligomerization domain containing 1 10392 ENSG00000106100
64  ENSG00000155849 NA ELMO1 engulfment and cell motility 1 9844 ENSG00000155849
65  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
66  ENSG00000079313 NA REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 57455 ENSG00000079313
67  ENSG00000136044 NA APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 55198 ENSG00000136044
68  ENSG00000135678 NA CPM carboxypeptidase M 1368 ENSG00000135678
69  ENSG00000008130 NA NADK NAD kinase 65220 ENSG00000008130
70  ENSG00000088387 NA DOCK9 dedicator of cytokinesis 9 23348 ENSG00000088387
71  ENSG00000148175 NA STOM stomatin 2040 ENSG00000148175


Database:cellular component       Name:Golgi apparatus part       ID:GO:0044431
C=672; O=6; E=3.03; R=1.98; rawP=0.0829; adjP=0.5660
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000184005 NA ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 256435 ENSG00000184005
2  ENSG00000131386 NA GALNTL2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2 117248 ENSG00000131386
3  ENSG00000113384 NA GOLPH3 golgi phosphoprotein 3 (coat-protein) 64083 ENSG00000113384
4  ENSG00000152661 NA GJA1 gap junction protein, alpha 1, 43kDa 2697 ENSG00000152661
5  ENSG00000082996 NA RNF13 ring finger protein 13 11342 ENSG00000082996
6  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001


Database:cellular component       Name:nuclear membrane       ID:GO:0031965
C=190; O=3; E=0.86; R=3.50; rawP=0.0547; adjP=0.5660
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000113384 NA GOLPH3 golgi phosphoprotein 3 (coat-protein) 64083 ENSG00000113384
2  ENSG00000082996 NA RNF13 ring finger protein 13 11342 ENSG00000082996
3  ENSG00000146457 NA WTAP Wilms tumor 1 associated protein 9589 ENSG00000146457


Database:cellular component       Name:Golgi apparatus       ID:GO:0005794
C=1180; O=9; E=5.33; R=1.69; rawP=0.0836; adjP=0.5660
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000129657 NA SEC14L1 SEC14-like 1 (S. cerevisiae) 6397 ENSG00000129657
2  ENSG00000152661 NA GJA1 gap junction protein, alpha 1, 43kDa 2697 ENSG00000152661
3  ENSG00000184005 NA ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 256435 ENSG00000184005
4  ENSG00000131386 NA GALNTL2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2 117248 ENSG00000131386
5  ENSG00000113384 NA GOLPH3 golgi phosphoprotein 3 (coat-protein) 64083 ENSG00000113384
6  ENSG00000156313 NA RPGR retinitis pigmentosa GTPase regulator 6103 ENSG00000156313
7  ENSG00000082996 NA RNF13 ring finger protein 13 11342 ENSG00000082996
8  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001
9  ENSG00000135378 NA PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 79056 ENSG00000135378


Database:cellular component       Name:Golgi membrane       ID:GO:0000139
C=553; O=6; E=2.50; R=2.40; rawP=0.0387; adjP=0.5660
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000184005 NA ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 256435 ENSG00000184005
2  ENSG00000131386 NA GALNTL2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2 117248 ENSG00000131386
3  ENSG00000113384 NA GOLPH3 golgi phosphoprotein 3 (coat-protein) 64083 ENSG00000113384
4  ENSG00000152661 NA GJA1 gap junction protein, alpha 1, 43kDa 2697 ENSG00000152661
5  ENSG00000082996 NA RNF13 ring finger protein 13 11342 ENSG00000082996
6  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001


Database:cellular component       Name:cell part       ID:GO:0044464
C=14643; O=71; E=66.12; R=1.07; rawP=0.0679; adjP=0.5660
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
2  ENSG00000129657 NA SEC14L1 SEC14-like 1 (S. cerevisiae) 6397 ENSG00000129657
3  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
4  ENSG00000155508 NA CNOT8 CCR4-NOT transcription complex, subunit 8 9337 ENSG00000155508
5  ENSG00000101276 NA SLC52A3 solute carrier family 52, riboflavin transporter, member 3 113278 ENSG00000101276
6  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
7  ENSG00000135821 NA GLUL glutamate-ammonia ligase 2752 ENSG00000135821
8  ENSG00000179604 NA CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 23580 ENSG00000179604
9  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001
10  ENSG00000117461 NA PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 8503 ENSG00000117461
11  ENSG00000069122 NA GPR116 G protein-coupled receptor 116 221395 ENSG00000069122
12  ENSG00000027697 NA IFNGR1 interferon gamma receptor 1 3459 ENSG00000027697
13  ENSG00000023445 NA BIRC3 baculoviral IAP repeat containing 3 330 ENSG00000023445
14  ENSG00000152661 NA GJA1 gap junction protein, alpha 1, 43kDa 2697 ENSG00000152661
15  ENSG00000135503 NA ACVR1B activin A receptor, type IB 91 ENSG00000135503
16  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
17  ENSG00000117707 NA PROX1 prospero homeobox 1 5629 ENSG00000117707
18  ENSG00000113384 NA GOLPH3 golgi phosphoprotein 3 (coat-protein) 64083 ENSG00000113384
19  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
20  ENSG00000196136 NA SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 12 ENSG00000196136
21  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
22  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
23  ENSG00000096060 NA FKBP5 FK506 binding protein 5 2289 ENSG00000096060
24  ENSG00000131386 NA GALNTL2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2 117248 ENSG00000131386
25  ENSG00000115602 NA IL1RL1 interleukin 1 receptor-like 1 9173 ENSG00000115602
26  ENSG00000179921 NA GPBAR1 G protein-coupled bile acid receptor 1 151306 ENSG00000179921
27  ENSG00000171877 NA FRMD5 FERM domain containing 5 84978 ENSG00000171877
28  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593
29  ENSG00000187513 NA GJA4 gap junction protein, alpha 4, 37kDa 2701 ENSG00000187513
30  ENSG00000184205 NA TSPYL2 TSPY-like 2 64061 ENSG00000184205
31  ENSG00000143882 NA ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 245973 ENSG00000143882
32  ENSG00000163389 NA POGLUT1 protein O-glucosyltransferase 1 56983 ENSG00000163389
33  ENSG00000205336 NA GPR56 G protein-coupled receptor 56 9289 ENSG00000205336
34  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
35  ENSG00000157150 NA TIMP4 TIMP metallopeptidase inhibitor 4 7079 ENSG00000157150
36  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
37  ENSG00000187193 NA MT1X metallothionein 1X 4501 ENSG00000187193
38  ENSG00000115604 NA IL18R1 interleukin 18 receptor 1 8809 ENSG00000115604
39  ENSG00000135378 NA PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 79056 ENSG00000135378
40  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
41  ENSG00000105245 NA NUMBL numb homolog (Drosophila)-like 9253 ENSG00000105245
42  ENSG00000134369 NA NAV1 neuron navigator 1 89796 ENSG00000134369
43  ENSG00000123095 NA BHLHE41 basic helix-loop-helix family, member e41 79365 ENSG00000123095
44  ENSG00000205364 NA MT1M metallothionein 1M 4499 ENSG00000205364
45  ENSG00000183580 NA FBXL7 F-box and leucine-rich repeat protein 7 23194 ENSG00000183580
46  ENSG00000136160 NA EDNRB endothelin receptor type B 1910 ENSG00000136160
47  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
48  ENSG00000086544 NA ITPKC inositol-trisphosphate 3-kinase C 80271 ENSG00000086544
49  ENSG00000186141 NA POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 10623 ENSG00000186141
50  ENSG00000156313 NA RPGR retinitis pigmentosa GTPase regulator 6103 ENSG00000156313
51  ENSG00000221869 NA CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1052 ENSG00000221869
52  ENSG00000154217 NA PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 26207 ENSG00000154217
53  ENSG00000156453 NA PCDH1 protocadherin 1 5097 ENSG00000156453
54  ENSG00000118985 NA ELL2 elongation factor, RNA polymerase II, 2 22936 ENSG00000118985
55  ENSG00000164951 NA PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 54704 ENSG00000164951
56  ENSG00000162174 NA ASRGL1 asparaginase like 1 80150 ENSG00000162174
57  ENSG00000146457 NA WTAP Wilms tumor 1 associated protein 9589 ENSG00000146457
58  ENSG00000184005 NA ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 256435 ENSG00000184005
59  ENSG00000108622 NA ICAM2 intercellular adhesion molecule 2 3384 ENSG00000108622
60  ENSG00000082996 NA RNF13 ring finger protein 13 11342 ENSG00000082996
61  ENSG00000172216 NA CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1051 ENSG00000172216
62  ENSG00000101187 NA SLCO4A1 solute carrier organic anion transporter family, member 4A1 28231 ENSG00000101187
63  ENSG00000106100 NA NOD1 nucleotide-binding oligomerization domain containing 1 10392 ENSG00000106100
64  ENSG00000155849 NA ELMO1 engulfment and cell motility 1 9844 ENSG00000155849
65  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
66  ENSG00000079313 NA REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 57455 ENSG00000079313
67  ENSG00000136044 NA APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 55198 ENSG00000136044
68  ENSG00000135678 NA CPM carboxypeptidase M 1368 ENSG00000135678
69  ENSG00000008130 NA NADK NAD kinase 65220 ENSG00000008130
70  ENSG00000088387 NA DOCK9 dedicator of cytokinesis 9 23348 ENSG00000088387
71  ENSG00000148175 NA STOM stomatin 2040 ENSG00000148175


Database:cellular component       Name:cytoplasm       ID:GO:0005737
C=9130; O=50; E=41.23; R=1.21; rawP=0.0282; adjP=0.5660
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111725 NA PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 5564 ENSG00000111725
2  ENSG00000129657 NA SEC14L1 SEC14-like 1 (S. cerevisiae) 6397 ENSG00000129657
3  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
4  ENSG00000163389 NA POGLUT1 protein O-glucosyltransferase 1 56983 ENSG00000163389
5  ENSG00000143882 NA ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 245973 ENSG00000143882
6  ENSG00000184205 NA TSPYL2 TSPY-like 2 64061 ENSG00000184205
7  ENSG00000155508 NA CNOT8 CCR4-NOT transcription complex, subunit 8 9337 ENSG00000155508
8  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
9  ENSG00000090376 NA IRAK3 interleukin-1 receptor-associated kinase 3 11213 ENSG00000090376
10  ENSG00000157150 NA TIMP4 TIMP metallopeptidase inhibitor 4 7079 ENSG00000157150
11  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
12  ENSG00000187193 NA MT1X metallothionein 1X 4501 ENSG00000187193
13  ENSG00000135821 NA GLUL glutamate-ammonia ligase 2752 ENSG00000135821
14  ENSG00000135378 NA PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 79056 ENSG00000135378
15  ENSG00000179604 NA CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 23580 ENSG00000179604
16  ENSG00000068001 NA HYAL2 hyaluronoglucosaminidase 2 8692 ENSG00000068001
17  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
18  ENSG00000105245 NA NUMBL numb homolog (Drosophila)-like 9253 ENSG00000105245
19  ENSG00000134369 NA NAV1 neuron navigator 1 89796 ENSG00000134369
20  ENSG00000205364 NA MT1M metallothionein 1M 4499 ENSG00000205364
21  ENSG00000117461 NA PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 8503 ENSG00000117461
22  ENSG00000183580 NA FBXL7 F-box and leucine-rich repeat protein 7 23194 ENSG00000183580
23  ENSG00000086544 NA ITPKC inositol-trisphosphate 3-kinase C 80271 ENSG00000086544
24  ENSG00000156313 NA RPGR retinitis pigmentosa GTPase regulator 6103 ENSG00000156313
25  ENSG00000154217 NA PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 26207 ENSG00000154217
26  ENSG00000023445 NA BIRC3 baculoviral IAP repeat containing 3 330 ENSG00000023445
27  ENSG00000152661 NA GJA1 gap junction protein, alpha 1, 43kDa 2697 ENSG00000152661
28  ENSG00000162174 NA ASRGL1 asparaginase like 1 80150 ENSG00000162174
29  ENSG00000164951 NA PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 54704 ENSG00000164951
30  ENSG00000183943 NA PRKX protein kinase, X-linked 5613 ENSG00000183943
31  ENSG00000117707 NA PROX1 prospero homeobox 1 5629 ENSG00000117707
32  ENSG00000184005 NA ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 256435 ENSG00000184005
33  ENSG00000113384 NA GOLPH3 golgi phosphoprotein 3 (coat-protein) 64083 ENSG00000113384
34  ENSG00000082996 NA RNF13 ring finger protein 13 11342 ENSG00000082996
35  ENSG00000172216 NA CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1051 ENSG00000172216
36  ENSG00000106100 NA NOD1 nucleotide-binding oligomerization domain containing 1 10392 ENSG00000106100
37  ENSG00000155849 NA ELMO1 engulfment and cell motility 1 9844 ENSG00000155849
38  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
39  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
40  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
41  ENSG00000136044 NA APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 55198 ENSG00000136044
42  ENSG00000135678 NA CPM carboxypeptidase M 1368 ENSG00000135678
43  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
44  ENSG00000096060 NA FKBP5 FK506 binding protein 5 2289 ENSG00000096060
45  ENSG00000131386 NA GALNTL2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2 117248 ENSG00000131386
46  ENSG00000008130 NA NADK NAD kinase 65220 ENSG00000008130
47  ENSG00000171877 NA FRMD5 FERM domain containing 5 84978 ENSG00000171877
48  ENSG00000088387 NA DOCK9 dedicator of cytokinesis 9 23348 ENSG00000088387
49  ENSG00000148175 NA STOM stomatin 2040 ENSG00000148175
50  ENSG00000179593 NA ALOX15B arachidonate 15-lipoxygenase, type B 247 ENSG00000179593




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).